Hollow Fiber and Its Application

1.Pengenalan

Hollow fiber membrane is a self-supporting membrane that looks like a fiber and has a hollow structure inside. It uses pressure as the driving force to filter out particles, bacteria or intercept targets, and has selective permeability. The hollow fiber membrane has an open flow channel, low shear force and high dust holding capacity. It can directly process complex feed liquids with high solid content and high viscosity.

2. Aplikasi

A. Protein: hollow fiber can be used for separation and purification of protein, such as serum albumin, immunoglobulin, cytokines, etc. Among them, in the preparation process of serum albumin, steps such as ion exchange and affinity chromatography can be performed using hollow fibers to improve purity and yield.

B. Antibodies: hollow fiber can be used for the separation and purification of antibodies, such as monoclonal antibodies and polyclonal antibodies. Among them, in the preparation process of monoclonal antibodies, hollow fibers can be used for steps such as ion exchange and affinity chromatography to improve purity and yield.

C. Vaccines: Hollow fiber can be used in the preparation of vaccines, such as virus vaccines and bacterial vaccines. Among them, in the preparation process of virus vaccines, hollow fibers can be used for steps such as ion exchange and gel filtration to remove impurities and improve virus purity.